Review



human hepatocellular carcinoma hepg2 c3a  (ATCC)


Bioz Verified Symbol ATCC is a verified supplier
Bioz Manufacturer Symbol ATCC manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 99
      Buy from Supplier

    Structured Review

    ATCC human hepatocellular carcinoma hepg2 c3a
    Effect of 10 Gy X‐ray on viability of NIH‐3T3, B16.F10, MDA‐MB‐231, and <t>HepG2</t> cells. Blue: untreated controls; Pink: irradiated cells. Cell counts were conducted at 24, 48, and 72 h post‐treatment. Statistical analysis was performed using two‐way ANOVA with Tukey's post hoc test: p < 0.05 (*), p < 0.005 (**), p < 0.0005 (***), p < 0.0001 (****), n = 3. Note: Y ‐axes are scaled independently for each cell line to account for differences in baseline growth, allowing clearer visualization of treatment effects. Tumor cell counts and representative images can be found in Appendix Table and Figure .
    Human Hepatocellular Carcinoma Hepg2 C3a, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 29907 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+c3a/Hep+G2/pmc13112599-173-15-25
    Average 99 stars, based on 29907 article reviews
    human hepatocellular carcinoma hepg2 c3a - by Bioz Stars, 2026-09
    99/100 stars

    Images

    1) Product Images from "Synergistic Effects of IMP‐1700, Ciprofloxacin, and X‐Ray Radiation in Bacteria and Mammalian Cell Lines: Implications for Use in Antimicrobial‐Resistant Bacteria"

    Article Title: Synergistic Effects of IMP‐1700, Ciprofloxacin, and X‐Ray Radiation in Bacteria and Mammalian Cell Lines: Implications for Use in Antimicrobial‐Resistant Bacteria

    Journal: MicrobiologyOpen

    doi: 10.1002/mbo3.70270

    Effect of 10 Gy X‐ray on viability of NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells. Blue: untreated controls; Pink: irradiated cells. Cell counts were conducted at 24, 48, and 72 h post‐treatment. Statistical analysis was performed using two‐way ANOVA with Tukey's post hoc test: p < 0.05 (*), p < 0.005 (**), p < 0.0005 (***), p < 0.0001 (****), n = 3. Note: Y ‐axes are scaled independently for each cell line to account for differences in baseline growth, allowing clearer visualization of treatment effects. Tumor cell counts and representative images can be found in Appendix Table and Figure .
    Figure Legend Snippet: Effect of 10 Gy X‐ray on viability of NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells. Blue: untreated controls; Pink: irradiated cells. Cell counts were conducted at 24, 48, and 72 h post‐treatment. Statistical analysis was performed using two‐way ANOVA with Tukey's post hoc test: p < 0.05 (*), p < 0.005 (**), p < 0.0005 (***), p < 0.0001 (****), n = 3. Note: Y ‐axes are scaled independently for each cell line to account for differences in baseline growth, allowing clearer visualization of treatment effects. Tumor cell counts and representative images can be found in Appendix Table and Figure .

    Techniques Used: Irradiation

    Images of untreated NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells and cells exposed to X‐ray. Scalebar: 300 µm.
    Figure Legend Snippet: Images of untreated NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells and cells exposed to X‐ray. Scalebar: 300 µm.

    Techniques Used:

    Viability of NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells after treatment with IMP‐1700 (5 µM), ciprofloxacin (CPX) (15 µM), their combination, or DMSO, with and without 10 Gy X‐ray. Cell counts were measured at 24, 48, and 72 h post‐treatment. Statistical significance assessed via two‐way ANOVA and Tukey's post hoc test: p < 0.05 (*), p < 0.005 (**), p < 0.0005 (***), p < 0.0001 (****), n = 3. Significant differences are only shown compared to untreated or 10 Gy. Tumor cell count values and images are available in Appendix Table and Figure , , , .
    Figure Legend Snippet: Viability of NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells after treatment with IMP‐1700 (5 µM), ciprofloxacin (CPX) (15 µM), their combination, or DMSO, with and without 10 Gy X‐ray. Cell counts were measured at 24, 48, and 72 h post‐treatment. Statistical significance assessed via two‐way ANOVA and Tukey's post hoc test: p < 0.05 (*), p < 0.005 (**), p < 0.0005 (***), p < 0.0001 (****), n = 3. Significant differences are only shown compared to untreated or 10 Gy. Tumor cell count values and images are available in Appendix Table and Figure , , , .

    Techniques Used: Cell Characterization

    Images of NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells treated with IMP‐1700, with and without X‐ray. Scalebar: 300 µm.
    Figure Legend Snippet: Images of NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells treated with IMP‐1700, with and without X‐ray. Scalebar: 300 µm.

    Techniques Used:

    Images of NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells treated with ciprofloxacin (CPX), with and without X‐ray. Scalebar: 300 µm.
    Figure Legend Snippet: Images of NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells treated with ciprofloxacin (CPX), with and without X‐ray. Scalebar: 300 µm.

    Techniques Used:

    Images of NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells treated with IMP‐1700 and ciprofloxacin (CPX), with and without X‐ray. Scalebar: 300 µm.
    Figure Legend Snippet: Images of NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells treated with IMP‐1700 and ciprofloxacin (CPX), with and without X‐ray. Scalebar: 300 µm.

    Techniques Used:

    Images of NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells treated with DMSO, with and without X‐ray. Scalebar: 300 µm.
    Figure Legend Snippet: Images of NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells treated with DMSO, with and without X‐ray. Scalebar: 300 µm.

    Techniques Used:

    Related Articles

    Binding Assay:


    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation.
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/ mL streptomycin.

    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/mL streptomycin.

    Article Title: Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
    Article Snippet: Human: C3A, <10 Passages , ATCC , Cat#: CRL-10741.

    Activity Assay:


    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation.
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/ mL streptomycin.

    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/mL streptomycin.

    Article Title: Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
    Article Snippet: Human: C3A, <10 Passages , ATCC , Cat#: CRL-10741.

    SPR Assay:


    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation.
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/ mL streptomycin.

    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/mL streptomycin.

    Article Title: Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
    Article Snippet: Human: C3A, <10 Passages , ATCC , Cat#: CRL-10741.

    Analogues:


    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation.
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/ mL streptomycin.

    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/mL streptomycin.

    Article Title: Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
    Article Snippet: Human: C3A, <10 Passages , ATCC , Cat#: CRL-10741.

    Solubility:


    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation.
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/ mL streptomycin.

    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/mL streptomycin.

    Article Title: Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
    Article Snippet: Human: C3A, <10 Passages , ATCC , Cat#: CRL-10741.

    Virus:


    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation.
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/ mL streptomycin.

    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/mL streptomycin.

    Article Title: Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
    Article Snippet: Human: C3A, <10 Passages , ATCC , Cat#: CRL-10741.

    Recombinant:


    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation.
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/ mL streptomycin.

    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/mL streptomycin.

    Article Title: Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
    Article Snippet: Human: C3A, <10 Passages , ATCC , Cat#: CRL-10741.

    Mass Spectrometry:


    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation.
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/ mL streptomycin.

    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/mL streptomycin.

    Article Title: Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
    Article Snippet: Human: C3A, <10 Passages , ATCC , Cat#: CRL-10741.

    Protease Inhibitor:


    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation.
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/ mL streptomycin.

    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/mL streptomycin.

    Article Title: Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
    Article Snippet: Human: C3A, <10 Passages , ATCC , Cat#: CRL-10741.

    Western Blot:


    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation.
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/ mL streptomycin.

    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/mL streptomycin.

    Article Title: Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
    Article Snippet: Human: C3A, <10 Passages , ATCC , Cat#: CRL-10741.

    cDNA Synthesis:


    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation.
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/ mL streptomycin.

    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/mL streptomycin.

    Article Title: Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
    Article Snippet: Human: C3A, <10 Passages , ATCC , Cat#: CRL-10741.

    shRNA:


    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation.
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/ mL streptomycin.

    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/mL streptomycin.

    Article Title: Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
    Article Snippet: Human: C3A, <10 Passages , ATCC , Cat#: CRL-10741.

    Plasmid Preparation:


    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation.
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/ mL streptomycin.

    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/mL streptomycin.

    Article Title: Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
    Article Snippet: Human: C3A, <10 Passages , ATCC , Cat#: CRL-10741.

    Software:


    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation.
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/ mL streptomycin.

    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/mL streptomycin.

    Article Title: Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
    Article Snippet: Human: C3A, <10 Passages , ATCC , Cat#: CRL-10741.

    Phospho-proteomics:


    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation.
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/ mL streptomycin.

    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/mL streptomycin.

    Article Title: Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
    Article Snippet: Human: C3A, <10 Passages , ATCC , Cat#: CRL-10741.

    Real-time Polymerase Chain Reaction:


    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation.
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/ mL streptomycin.

    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/mL streptomycin.

    Article Title: Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
    Article Snippet: Human: C3A, <10 Passages , ATCC , Cat#: CRL-10741.

    High Throughput Screening Assay:


    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation.
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/ mL streptomycin.

    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation
    Article Snippet: Human C3A obtained from ATCC were maintained in Eagle’s minimum Essential medium (ATCC) supplemented with 2 mM glutamine, 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/mL streptomycin.

    Article Title: Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
    Article Snippet: Human: C3A, <10 Passages , ATCC , Cat#: CRL-10741.



    Similar Products

    human hepatocellular carcinoma hepg2 c3a  (ATCC)
    99
    ATCC human hepatocellular carcinoma hepg2 c3a
    Effect of 10 Gy X‐ray on viability of NIH‐3T3, B16.F10, MDA‐MB‐231, and <t>HepG2</t> cells. Blue: untreated controls; Pink: irradiated cells. Cell counts were conducted at 24, 48, and 72 h post‐treatment. Statistical analysis was performed using two‐way ANOVA with Tukey's post hoc test: p < 0.05 (*), p < 0.005 (**), p < 0.0005 (***), p < 0.0001 (****), n = 3. Note: Y ‐axes are scaled independently for each cell line to account for differences in baseline growth, allowing clearer visualization of treatment effects. Tumor cell counts and representative images can be found in Appendix Table and Figure .
    Human Hepatocellular Carcinoma Hepg2 C3a, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+c3a/Hep+G2/pmc13112599-173-15-25
    Average 99 stars, based on 1 article reviews
    human hepatocellular carcinoma hepg2 c3a - by Bioz Stars, 2026-09
    99/100 stars
    		  Buy from Supplier
    human c3a elisa kit  (Hycult Biotech)
    94
    Hycult Biotech human c3a elisa kit
    Effect of 10 Gy X‐ray on viability of NIH‐3T3, B16.F10, MDA‐MB‐231, and <t>HepG2</t> cells. Blue: untreated controls; Pink: irradiated cells. Cell counts were conducted at 24, 48, and 72 h post‐treatment. Statistical analysis was performed using two‐way ANOVA with Tukey's post hoc test: p < 0.05 (*), p < 0.005 (**), p < 0.0005 (***), p < 0.0001 (****), n = 3. Note: Y ‐axes are scaled independently for each cell line to account for differences in baseline growth, allowing clearer visualization of treatment effects. Tumor cell counts and representative images can be found in Appendix Table and Figure .
    Human C3a Elisa Kit, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+c3a/C3a%2C+Human%2C+ELISA+kit/us12595270-839-0-4
    Average 94 stars, based on 1 article reviews
    human c3a elisa kit - by Bioz Stars, 2026-09
    94/100 stars
    		  Buy from Supplier
    human complement c3a elisa kit invitrogen bms2089 human complement c5a elisa kit invitrogen bms2088 kapa hifi hotstart readymix kapa biosystems  (Roche)
    99
    Roche human complement c3a elisa kit invitrogen bms2089 human complement c5a elisa kit invitrogen bms2088 kapa hifi hotstart readymix kapa biosystems
    Effect of 10 Gy X‐ray on viability of NIH‐3T3, B16.F10, MDA‐MB‐231, and <t>HepG2</t> cells. Blue: untreated controls; Pink: irradiated cells. Cell counts were conducted at 24, 48, and 72 h post‐treatment. Statistical analysis was performed using two‐way ANOVA with Tukey's post hoc test: p < 0.05 (*), p < 0.005 (**), p < 0.0005 (***), p < 0.0001 (****), n = 3. Note: Y ‐axes are scaled independently for each cell line to account for differences in baseline growth, allowing clearer visualization of treatment effects. Tumor cell counts and representative images can be found in Appendix Table and Figure .
    Human Complement C3a Elisa Kit Invitrogen Bms2089 Human Complement C5a Elisa Kit Invitrogen Bms2088 Kapa Hifi Hotstart Readymix Kapa Biosystems, supplied by Roche, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+c3a/KAPA+HiFi+Kit/pm41997144-265-207-225
    Average 99 stars, based on 1 article reviews
    human complement c3a elisa kit invitrogen bms2089 human complement c5a elisa kit invitrogen bms2088 kapa hifi hotstart readymix kapa biosystems - by Bioz Stars, 2026-09
    99/100 stars
    		  Buy from Supplier
    human c3a  (ATCC)
    96
    ATCC human c3a
    Effect of 10 Gy X‐ray on viability of NIH‐3T3, B16.F10, MDA‐MB‐231, and <t>HepG2</t> cells. Blue: untreated controls; Pink: irradiated cells. Cell counts were conducted at 24, 48, and 72 h post‐treatment. Statistical analysis was performed using two‐way ANOVA with Tukey's post hoc test: p < 0.05 (*), p < 0.005 (**), p < 0.0005 (***), p < 0.0001 (****), n = 3. Note: Y ‐axes are scaled independently for each cell line to account for differences in baseline growth, allowing clearer visualization of treatment effects. Tumor cell counts and representative images can be found in Appendix Table and Figure .
    Human C3a, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+c3a/C3A/pm41771535-188-0-4
    Average 96 stars, based on 1 article reviews
    human c3a - by Bioz Stars, 2026-09
    96/100 stars
    		  Buy from Supplier
    human c3a hepg2 c3a cells  (ATCC)
    99
    ATCC human c3a hepg2 c3a cells
    Binding site view of the PZ-3022 (1) PANK3 AMP-PNP complex (PDB ID: 6PE6 ) showing the spatial proximity of the cyclopropyl to the ATP-binding pocket of the enzyme. B) Pantazine PZ-3890 CoA elevation dose response in human <t>C3A</t> cells demonstrating a “hook effect” and an optimal activity window of 1–30 μM for this compound.
    Human C3a Hepg2 C3a Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+c3a/Hep+G2/pmc12990099-167-0-4
    Average 99 stars, based on 1 article reviews
    human c3a hepg2 c3a cells - by Bioz Stars, 2026-09
    99/100 stars
    		  Buy from Supplier
    cells  (ATCC)
    94
    ATCC cells
    Binding site view of the PZ-3022 (1) PANK3 AMP-PNP complex (PDB ID: 6PE6 ) showing the spatial proximity of the cyclopropyl to the ATP-binding pocket of the enzyme. B) Pantazine PZ-3890 CoA elevation dose response in human <t>C3A</t> cells demonstrating a “hook effect” and an optimal activity window of 1–30 μM for this compound.
    Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+c3a/C3A+(HepG2%2FC3A)%3B+Hepatocellular+Carcinoma%3B+Human/pm41735377-214-25-29
    Average 94 stars, based on 1 article reviews
    cells - by Bioz Stars, 2026-09
    94/100 stars
    		  Buy from Supplier

    Image Search Results


    Effect of 10 Gy X‐ray on viability of NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells. Blue: untreated controls; Pink: irradiated cells. Cell counts were conducted at 24, 48, and 72 h post‐treatment. Statistical analysis was performed using two‐way ANOVA with Tukey's post hoc test: p < 0.05 (*), p < 0.005 (**), p < 0.0005 (***), p < 0.0001 (****), n = 3. Note: Y ‐axes are scaled independently for each cell line to account for differences in baseline growth, allowing clearer visualization of treatment effects. Tumor cell counts and representative images can be found in Appendix Table and Figure .

    Journal: MicrobiologyOpen

    Article Title: Synergistic Effects of IMP‐1700, Ciprofloxacin, and X‐Ray Radiation in Bacteria and Mammalian Cell Lines: Implications for Use in Antimicrobial‐Resistant Bacteria

    doi: 10.1002/mbo3.70270

    Figure Lengend Snippet: Effect of 10 Gy X‐ray on viability of NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells. Blue: untreated controls; Pink: irradiated cells. Cell counts were conducted at 24, 48, and 72 h post‐treatment. Statistical analysis was performed using two‐way ANOVA with Tukey's post hoc test: p < 0.05 (*), p < 0.005 (**), p < 0.0005 (***), p < 0.0001 (****), n = 3. Note: Y ‐axes are scaled independently for each cell line to account for differences in baseline growth, allowing clearer visualization of treatment effects. Tumor cell counts and representative images can be found in Appendix Table and Figure .

    Article Snippet: The tumor cell lines, mouse melanoma B16.F10 (CRL‐6475, ATCC), human breast cancer MB‐MDA‐231 (CRM‐HTB‐26, ATCC), human hepatocellular carcinoma HepG2 C3A (a derivative of HepG2, CRL‐3581, ATCC), as well as the noncancerous mouse fibroblast cell line NIH‐3T3 (CRL‐1658, ATCC), were cultivated at 37°C, 5% CO2.

    Techniques: Irradiation

    Images of untreated NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells and cells exposed to X‐ray. Scalebar: 300 µm.

    Journal: MicrobiologyOpen

    Article Title: Synergistic Effects of IMP‐1700, Ciprofloxacin, and X‐Ray Radiation in Bacteria and Mammalian Cell Lines: Implications for Use in Antimicrobial‐Resistant Bacteria

    doi: 10.1002/mbo3.70270

    Figure Lengend Snippet: Images of untreated NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells and cells exposed to X‐ray. Scalebar: 300 µm.

    Article Snippet: The tumor cell lines, mouse melanoma B16.F10 (CRL‐6475, ATCC), human breast cancer MB‐MDA‐231 (CRM‐HTB‐26, ATCC), human hepatocellular carcinoma HepG2 C3A (a derivative of HepG2, CRL‐3581, ATCC), as well as the noncancerous mouse fibroblast cell line NIH‐3T3 (CRL‐1658, ATCC), were cultivated at 37°C, 5% CO2.

    Techniques:

    Viability of NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells after treatment with IMP‐1700 (5 µM), ciprofloxacin (CPX) (15 µM), their combination, or DMSO, with and without 10 Gy X‐ray. Cell counts were measured at 24, 48, and 72 h post‐treatment. Statistical significance assessed via two‐way ANOVA and Tukey's post hoc test: p < 0.05 (*), p < 0.005 (**), p < 0.0005 (***), p < 0.0001 (****), n = 3. Significant differences are only shown compared to untreated or 10 Gy. Tumor cell count values and images are available in Appendix Table and Figure , , , .

    Journal: MicrobiologyOpen

    Article Title: Synergistic Effects of IMP‐1700, Ciprofloxacin, and X‐Ray Radiation in Bacteria and Mammalian Cell Lines: Implications for Use in Antimicrobial‐Resistant Bacteria

    doi: 10.1002/mbo3.70270

    Figure Lengend Snippet: Viability of NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells after treatment with IMP‐1700 (5 µM), ciprofloxacin (CPX) (15 µM), their combination, or DMSO, with and without 10 Gy X‐ray. Cell counts were measured at 24, 48, and 72 h post‐treatment. Statistical significance assessed via two‐way ANOVA and Tukey's post hoc test: p < 0.05 (*), p < 0.005 (**), p < 0.0005 (***), p < 0.0001 (****), n = 3. Significant differences are only shown compared to untreated or 10 Gy. Tumor cell count values and images are available in Appendix Table and Figure , , , .

    Article Snippet: The tumor cell lines, mouse melanoma B16.F10 (CRL‐6475, ATCC), human breast cancer MB‐MDA‐231 (CRM‐HTB‐26, ATCC), human hepatocellular carcinoma HepG2 C3A (a derivative of HepG2, CRL‐3581, ATCC), as well as the noncancerous mouse fibroblast cell line NIH‐3T3 (CRL‐1658, ATCC), were cultivated at 37°C, 5% CO2.

    Techniques: Cell Characterization

    Images of NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells treated with IMP‐1700, with and without X‐ray. Scalebar: 300 µm.

    Journal: MicrobiologyOpen

    Article Title: Synergistic Effects of IMP‐1700, Ciprofloxacin, and X‐Ray Radiation in Bacteria and Mammalian Cell Lines: Implications for Use in Antimicrobial‐Resistant Bacteria

    doi: 10.1002/mbo3.70270

    Figure Lengend Snippet: Images of NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells treated with IMP‐1700, with and without X‐ray. Scalebar: 300 µm.

    Article Snippet: The tumor cell lines, mouse melanoma B16.F10 (CRL‐6475, ATCC), human breast cancer MB‐MDA‐231 (CRM‐HTB‐26, ATCC), human hepatocellular carcinoma HepG2 C3A (a derivative of HepG2, CRL‐3581, ATCC), as well as the noncancerous mouse fibroblast cell line NIH‐3T3 (CRL‐1658, ATCC), were cultivated at 37°C, 5% CO2.

    Techniques:

    Images of NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells treated with ciprofloxacin (CPX), with and without X‐ray. Scalebar: 300 µm.

    Journal: MicrobiologyOpen

    Article Title: Synergistic Effects of IMP‐1700, Ciprofloxacin, and X‐Ray Radiation in Bacteria and Mammalian Cell Lines: Implications for Use in Antimicrobial‐Resistant Bacteria

    doi: 10.1002/mbo3.70270

    Figure Lengend Snippet: Images of NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells treated with ciprofloxacin (CPX), with and without X‐ray. Scalebar: 300 µm.

    Article Snippet: The tumor cell lines, mouse melanoma B16.F10 (CRL‐6475, ATCC), human breast cancer MB‐MDA‐231 (CRM‐HTB‐26, ATCC), human hepatocellular carcinoma HepG2 C3A (a derivative of HepG2, CRL‐3581, ATCC), as well as the noncancerous mouse fibroblast cell line NIH‐3T3 (CRL‐1658, ATCC), were cultivated at 37°C, 5% CO2.

    Techniques:

    Images of NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells treated with IMP‐1700 and ciprofloxacin (CPX), with and without X‐ray. Scalebar: 300 µm.

    Journal: MicrobiologyOpen

    Article Title: Synergistic Effects of IMP‐1700, Ciprofloxacin, and X‐Ray Radiation in Bacteria and Mammalian Cell Lines: Implications for Use in Antimicrobial‐Resistant Bacteria

    doi: 10.1002/mbo3.70270

    Figure Lengend Snippet: Images of NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells treated with IMP‐1700 and ciprofloxacin (CPX), with and without X‐ray. Scalebar: 300 µm.

    Article Snippet: The tumor cell lines, mouse melanoma B16.F10 (CRL‐6475, ATCC), human breast cancer MB‐MDA‐231 (CRM‐HTB‐26, ATCC), human hepatocellular carcinoma HepG2 C3A (a derivative of HepG2, CRL‐3581, ATCC), as well as the noncancerous mouse fibroblast cell line NIH‐3T3 (CRL‐1658, ATCC), were cultivated at 37°C, 5% CO2.

    Techniques:

    Images of NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells treated with DMSO, with and without X‐ray. Scalebar: 300 µm.

    Journal: MicrobiologyOpen

    Article Title: Synergistic Effects of IMP‐1700, Ciprofloxacin, and X‐Ray Radiation in Bacteria and Mammalian Cell Lines: Implications for Use in Antimicrobial‐Resistant Bacteria

    doi: 10.1002/mbo3.70270

    Figure Lengend Snippet: Images of NIH‐3T3, B16.F10, MDA‐MB‐231, and HepG2 cells treated with DMSO, with and without X‐ray. Scalebar: 300 µm.

    Article Snippet: The tumor cell lines, mouse melanoma B16.F10 (CRL‐6475, ATCC), human breast cancer MB‐MDA‐231 (CRM‐HTB‐26, ATCC), human hepatocellular carcinoma HepG2 C3A (a derivative of HepG2, CRL‐3581, ATCC), as well as the noncancerous mouse fibroblast cell line NIH‐3T3 (CRL‐1658, ATCC), were cultivated at 37°C, 5% CO2.

    Techniques:

    Binding site view of the PZ-3022 (1) PANK3 AMP-PNP complex (PDB ID: 6PE6 ) showing the spatial proximity of the cyclopropyl to the ATP-binding pocket of the enzyme. B) Pantazine PZ-3890 CoA elevation dose response in human C3A cells demonstrating a “hook effect” and an optimal activity window of 1–30 μM for this compound.

    Journal: Journal of Medicinal Chemistry

    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation

    doi: 10.1021/acs.jmedchem.5c03452

    Figure Lengend Snippet: Binding site view of the PZ-3022 (1) PANK3 AMP-PNP complex (PDB ID: 6PE6 ) showing the spatial proximity of the cyclopropyl to the ATP-binding pocket of the enzyme. B) Pantazine PZ-3890 CoA elevation dose response in human C3A cells demonstrating a “hook effect” and an optimal activity window of 1–30 μM for this compound.

    Article Snippet: Human C3A (HepG2/C3A) cells (ATCC CRL-10741) were used for cellular assays.

    Techniques: Binding Assay, Activity Assay

    Correlation Analysis and Surface Plasmon Resonance. A. Correlation analysis of the difference between K i of PANK1β and PANK3 vs C3A CoA elevation. The green-to-red scale shows the difference in K i between PANK1β and PANK3, while the size of the circles indicates the level of CoA elevation. B–E Surface Plasmon Resonance trace showing the binding of 20 and 21 to PANK3 and PANK1β in the presence of 1 mM ATP. B. 20 with PANK3. C. 20 with PANK1β. D. 21 with PANK3. E. 21 with PANK1β. The green data line was fit to a kinetic model shown in the black line. The association ( K a ), dissociation ( K d ), binding equilibrium ( K D ) constants, residence time (RT), and response units (RU) are shown in each panel.

    Journal: Journal of Medicinal Chemistry

    Article Title: Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation

    doi: 10.1021/acs.jmedchem.5c03452

    Figure Lengend Snippet: Correlation Analysis and Surface Plasmon Resonance. A. Correlation analysis of the difference between K i of PANK1β and PANK3 vs C3A CoA elevation. The green-to-red scale shows the difference in K i between PANK1β and PANK3, while the size of the circles indicates the level of CoA elevation. B–E Surface Plasmon Resonance trace showing the binding of 20 and 21 to PANK3 and PANK1β in the presence of 1 mM ATP. B. 20 with PANK3. C. 20 with PANK1β. D. 21 with PANK3. E. 21 with PANK1β. The green data line was fit to a kinetic model shown in the black line. The association ( K a ), dissociation ( K d ), binding equilibrium ( K D ) constants, residence time (RT), and response units (RU) are shown in each panel.

    Article Snippet: Human C3A (HepG2/C3A) cells (ATCC CRL-10741) were used for cellular assays.

    Techniques: SPR Assay, Binding Assay